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DNA Topoisomerases and Cancer by Patrick Forterre (auth.), Yves Pommier (eds.) 2012

DNA Topoisomerases and Cancer

Details Of The Book

DNA Topoisomerases and Cancer

edition: 1 
Authors: ,   
serie: Cancer Drug Discovery and Development 
ISBN : 1461403227, 9781461403227 
publisher: Springer-Verlag New York 
publish year: 2012 
pages: 444 
language: English 
ebook format : PDF (It will be converted to PDF, EPUB OR AZW3 if requested by the user) 
file size: 5 MB 

price : $13.5 15 With 10% OFF

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You can Download DNA Topoisomerases and Cancer Book After Make Payment, According to the customer's request, this book can be converted into PDF, EPUB, AZW3 and DJVU formats.

Abstract Of The Book

Table Of Contents

Front Matter....Pages i-xi
Introduction and Historical Perspective....Pages 1-52
Human DNA Topoisomerase I: Structure, Enzymology and Biology....Pages 53-69
Mitochondrial Topoisomerases....Pages 71-85
Structure and Mechanism of Eukaryotic Type IIA Topoisomerases....Pages 87-101
Essential Functions of Topoisomerase IIIα in the Nucleus and Mitochondria....Pages 103-117
DNA Topoisomerase I and Illegitimate Recombination....Pages 119-143
Topoisomerase-Induced DNA Damage....Pages 145-154
Topoisomerases and Carcinogenesis: Topoisomerase IIIα and BLM....Pages 155-173
Topoisomerases Inhibitors: A Paradigm for Interfacial Inhibition....Pages 175-184
Topoisomerase I Inhibitors: Chemical Biology....Pages 185-210
Topoisomerase II Inhibitors: Chemical Biology....Pages 211-243
Topoisomerase I Inhibitors: Current Use and Prospects....Pages 245-277
Topoisomerase II Inhibitors: Current Use and Prospects....Pages 279-307
Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity....Pages 309-324
Mechanisms Regulating Cellular Responses to DNA Topoisomerase I-Targeted Agents....Pages 325-334
Tyrosyl-DNA-Phosphodiesterase....Pages 335-354
Ubiquitin and Ubiquitin-Like Proteins in Repair of Topoisomerase-Mediated DNA Damage....Pages 355-379
Repair of Topoisomerase II-Mediated DNA Damage: Fixing DNA Damage Arising from a Protein Covalently Trapped on DNA....Pages 381-407
Topoisomerases and Apoptosis....Pages 409-435
Back Matter....Pages 437-443

First 10 Pages Of the book

Comments Of The Book